Status:
COMPLETED
Vision Restoration Therapy (VRT) to Treat Non-Arteritic Anterior Ischemic Optic Neuropathy
Lead Sponsor:
Emory University
Conditions:
Non-Arteritic Anterior Ischemic Optic Neuropathy
Eligibility:
All Genders
30+ years
Phase:
NA
Brief Summary
The goal of this pilot study is to evaluate the effect of Vision Restoration Therapy, VRT, on the visual function of patients with unilateral or bilateral AION, who have good central vision (at least ...
Detailed Description
Anterior ischemic optic neuropathy (AION) is one of the most common causes of optic neuropathy after the age of 50. There is currently no available treatment and although up to 40% of patients have so...
Eligibility Criteria
Inclusion
- Patients seen by Dr Biousse or Dr Newman in the Neuro-Ophthalmology Unit at Emory University.
- Age ≥ 30 years.
- Diagnosis of non-arteritic ischemic optic neuropathy at least 6 months prior to inclusion.
- Uni- or bilateral AION (in case of bilateral AION, only one eye will be included in the study).
- Best corrected visual acuity of at least 20/60 in the study eye
- Altitudinal or arcuate visual field defect, splitting fixation by \>10 decibel difference above and below horizontal meridian.
- Stable visual function demonstrated by more than two stable visual acuity measurements and two automated visual field testings prior to inclusion in the study.
- Patient willing, and able, to spend 60 minutes-a-day for 6 months working on a computer.
Exclusion
- Patient cognitively or physically unable to perform reliable automated perimetry testing (on the 24-2 SITA Standard program) (which is grossly equivalent to the effort and attention needed to perform VRT daily at home).
- Other cause of optic neuropathy.
- Associated ocular disease requiring treatments or responsible for visual loss (such as untreated significant cataract, glaucoma, age related macular degeneration, etc…).
- Visual acuity worse than 20/60 in the study eye.
- Non-stable visual field defect on previous evaluations.
- Epilepsy.
Key Trial Info
Start Date :
August 1 2005
Trial Type :
INTERVENTIONAL
End Date :
April 1 2007
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00140491
Start Date
August 1 2005
End Date
April 1 2007
Last Update
October 23 2013
Active Locations (1)
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1
Emory Eye Center
Atlanta, Georgia, United States, 30322