Status:

COMPLETED

Nonpolymer- and Polymer-Based Drug-Eluting Stents for Restenosis (ISAR-TEST-1)

Lead Sponsor:

Deutsches Herzzentrum Muenchen

Collaborating Sponsors:

Bayerische Forschungsstiftung Muenchen

Conditions:

Coronary Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess the efficacy of nonpolymer-based rapamycin-eluting stent compared to standard polymer-based paclitaxel-eluting stent to reduce reblockage of coronary arteries.

Detailed Description

Drug-eluting stents represent a major advance in the treatment of restenosis. They have dramatically reduced the need of repeat revascularization procedures, and, thanks to the excellent results obtai...

Eligibility Criteria

Inclusion

  • Patients at least 18 years old
  • Stable or unstable angina or a positive stress test
  • "de novo" coronary artery lesions
  • Written informed consent

Exclusion

  • Myocardial infarction within 48 h. before enrollment
  • Target lesion located in left main trunk
  • Contraindication or known allergy to aspirin, heparin, thienopyridines, rapamycin, paclitaxel or stainless steel

Key Trial Info

Start Date :

March 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2005

Estimated Enrollment :

450 Patients enrolled

Trial Details

Trial ID

NCT00140530

Start Date

March 1 2004

End Date

June 1 2005

Last Update

January 11 2008

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Deutsches Herzzentrum Muenchen

Munich, Germany, 80636

2

First Medizinische Klinik, Klinikum rechts der Isar

Munich, Germany, 81675