Status:

COMPLETED

Pregabalin Epilepsy Add-On Trial

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Partial Seizures

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

To evaluate the efficacy of pregabalin as adjunctive therapy, using a flexible, optimized dose schedule with dose adjustment based on clinical response and tolerability, compared to placebo in subject...

Eligibility Criteria

Inclusion

  • Have a diagnosis of epilepsy with partial seizures (as defined in the ILAE Classification of Seizures) and be currently taking 1-3 AEDs
  • Have a minimum of 4 partial seizures occurring over at least 2 days during the 6-week baseline with no 28-day period free of partial seizures

Exclusion

  • Have a treatable cause of seizures
  • Are currently receiving treatment with CNS-active compounds (exception: single antidepressant, hypnotics, and standard AEDs), vigabatrin, Felbatol (felbamate), Neurontin (gabapentin)

Key Trial Info

Start Date :

October 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2006

Estimated Enrollment :

178 Patients enrolled

Trial Details

Trial ID

NCT00141258

Start Date

October 1 2005

End Date

August 1 2006

Last Update

January 22 2021

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Pfizer Investigational Site

Daegu, South Korea

2

Pfizer Investigational Site

Daejeon, South Korea

3

Pfizer Investigational Site

Gwangju, South Korea

4

Pfizer Investigational Site

Incheon, South Korea