Status:
COMPLETED
Feasibility Study of 2000 IU Per Day of Vitamin D for the Primary Prevention of Type 1 Diabetes
Lead Sponsor:
Canadian Diabetes Association
Collaborating Sponsors:
Manitoba Medical Service Foundation
Manitoba Institute of Child Health
Conditions:
Type 1 Diabetes
Eligibility:
All Genders
Up to 4 years
Phase:
PHASE1
Brief Summary
Type 1 diabetes is a common chronic disease of childhood. It is not yet preventable. Multiple daily injections of insulin, tests of blood sugar, and careful dietary planning are required lifelong to p...
Detailed Description
Type 1 diabetes is a multifactorial disease with both strong genetic and non-genetic components of disease susceptibility. The uniquely strong genetic risk factor region, the human leukocyte antigen r...
Eligibility Criteria
Inclusion
- HLA genotypes that increase risk of type 1 diabetes: heterozygous for DRB1\*03, DQA1\*0501, DQB1\*0201 / DRB1\*04, DQA1\*03011, DQB1\*0302 (DRB1\*04 ≠ \*0403 or related alleles), or homozygous for DRB1\*03, DQA1\*0501, DQB1\*0201, or homozygous for DRB1\*04, DQA1\*03011, DQB1\*0302 (DRB1\*04 ≠ \*0403 or related alleles).
Exclusion
- Premature, low birthweight, or major congenital malformations or serious chronic disease
Key Trial Info
Start Date :
November 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2007
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT00141986
Start Date
November 1 2003
End Date
March 1 2007
Last Update
April 26 2011
Active Locations (1)
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1
Manitoba Institute of Child Health
Winnipeg, Manitoba, Canada