Status:
TERMINATED
Opioid Agonist and Antagonist Effects on Opioid Dependence
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Collaborating Sponsors:
Johns Hopkins University
Conditions:
Opioid-Related Disorders
Eligibility:
All Genders
18-55 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to examine the acute agonist and antagonist effects of a full opioid agonist medication, an opioid antagonist medication, and a partial opioid agonist medication in indivi...
Detailed Description
The pharmacological effects of opioids in opioid dependent individuals can vary as a function of the characteristics of the opioid being studied (e.g., whether it is an agonist, partial agonist, or an...
Eligibility Criteria
Inclusion
- Active opioid dependence
- Qualifies for opioid agonist treatment (e.g., methadone or buprenorphine)
- Fulfills DSM-IV diagnostic criteria for opioid dependence
Exclusion
- Significant medical problems, including insulin dependent diabetes mellitus
- Non-substance use psychiatric disorders (e.g., schizophrenia)
- Currently seeking treatment for substance abuse
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2006
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00142727
Start Date
January 1 2004
End Date
February 1 2006
Last Update
January 12 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Johns Hopkins University (BPRU) Bayview Campus
Baltimore, Maryland, United States, 21224 6823