Status:

COMPLETED

Tramadol to Reduce Opioid Withdrawal Symptoms

Lead Sponsor:

National Institute on Drug Abuse (NIDA)

Conditions:

Opioid-Related Disorders

Eligibility:

All Genders

21-55 years

Phase:

PHASE2

Brief Summary

Individuals with opioid addiction often experience serious withdrawal symptoms that may make relapse unavoidable. Tramadol, a medication that is currently used to treat pain caused by chronic conditio...

Detailed Description

Opioid withdrawal symptoms are a major contributing factor for why opioid treatment programs often fail. Individuals with severe opioid withdrawal symptoms may experience shaking, muscle and bone pain...

Eligibility Criteria

Inclusion

  • Meets DSM-IV diagnostic criteria for opioid dependence
  • Is in good physical health
  • Qualifies for treatment with opioid agonist therapy (e.g., methadone)
  • If female, must have a negative pregnancy test prior to study entry

Exclusion

  • Evidence of significant medical illness (e.g., insulin dependent diabetes mellitus)
  • Evidence of significant psychiatric illness (e.g., schizophrenia)
  • Currently seeking treatment for substance abuse
  • Pregnant or breastfeeding

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2005

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00142896

Start Date

February 1 2005

End Date

December 1 2005

Last Update

January 12 2017

Active Locations (1)

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Johns Hopkins University (BPRU) Bayview Campus

Baltimore, Maryland, United States, 21224-6823