Status:

COMPLETED

Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody Titers

Lead Sponsor:

University of Chicago

Conditions:

End-Stage Kidney Disease

Eligibility:

All Genders

18-75 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to identify subjects who are highly sensitized with antibodies. It is difficult for these patients to find suitable kidneys. We propose to treat such patients to decrease ...

Detailed Description

Kidney transplantation is the desired treatment of choice in subjects with end-stage kidney disease (ESRD). The average waiting time for subjects to receive a "deceased donor" kidney transplant is 3-5...

Eligibility Criteria

Inclusion

  • Eighteen years or older,
  • On the waiting list for a kidney transplant list
  • On hemodialysis or peritoneal dialysis

Exclusion

  • Pregnant woman
  • Patients who need ongoing blood products
  • Patients with failed organs having active rejection
  • Other therapies to decrease PRA
  • Patients listed for multi-organ transplants (other than kidney-pancreas)

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00143741

Start Date

May 1 2005

End Date

July 1 2011

Last Update

January 10 2013

Active Locations (1)

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1

The University of Chicago

Chicago, Illinois, United States, 60637