Status:
UNKNOWN
TACT-NAGOYA: Therapeutic Angiogenesis Using Cell Transplantation
Lead Sponsor:
Nagoya University
Conditions:
Buerger Disease
Arteriosclerosis Obliterans
Eligibility:
All Genders
20-80 years
Brief Summary
Clinical studies have established that implantation of bone marrow mononuclear cells (BM-MNCs) or peripheral blood mononuclear cells (PB-MNCs) into ischaemic limbs increases collateral vessel formatio...
Eligibility Criteria
Inclusion
- Subjects who have chronic limb ischemia, including rest pain, non-healing ischemic ulcers, or both, and who are not candidates for nonsurgical or surgical revascularisation.
Exclusion
- Poorly controlled diabetes mellitus (hemoglobin A1c \[HbA1c\] \> 6.5% and proliferative retinopathy)
- Evidence of malignant disorder during the past 5 years
- Subjects who cannot survive more than 1 year with other complications
- Malignant rheumatic arthritis
Key Trial Info
Start Date :
August 1 2003
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00145262
Start Date
August 1 2003
Last Update
December 30 2005
Active Locations (1)
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1
Department of Cardiology, Nagoya University Graduate School of Medicine
Nagoya, Japan, 466-8550