Status:

COMPLETED

Study to Compare the Effect of Hormone Replacement Therapy (HRT) on Breast and Cardiovascular Metabolic Markers in Postmenopausal Women

Lead Sponsor:

Solvay Pharmaceuticals

Conditions:

Menopause

Eligibility:

FEMALE

45-65 years

Phase:

PHASE4

Brief Summary

This study is to evaluate the effects of continuously combined 17b-estradiol/dydrogesterone in comparison with tibolone on the breast metabolic markers, in particular the total insulin-like growth fac...

Eligibility Criteria

Inclusion

  • Natural or surgical postmenopausal amenorrhea since ≥ 12 months,
  • non hysterectomized women, complaining of at least 14 hot flushes per week

Exclusion

  • Known, suspected or history of breast cancer or hormone-dependent neoplasia,
  • undiagnosed genital bleeding,
  • venous or arterial history or presence of thromboembolism,
  • cerebrovascular disease

Key Trial Info

Start Date :

November 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2009

Estimated Enrollment :

135 Patients enrolled

Trial Details

Trial ID

NCT00145522

Start Date

November 1 2005

End Date

March 1 2009

Last Update

April 1 2009

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Site 8

Ancona, Italy

2

Site 15

Cagliari, Italy

3

Site 4

Catania, Italy

4

Site 9

Florence, Italy