Status:
TERMINATED
The Role of Fluorothymidine Positron Emission Tomography (FLT-PET) in Proliferation of Colorectal Liver Metastases
Lead Sponsor:
Radboud University Medical Center
Conditions:
Colorectal Neoplasms
Liver Neoplasms
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The aim of the study is to obtain information on FLT used in a PET-scan as a marker for the proliferation of colorectal liver metastases, so that the risk of recurrence can be identified in a noninvas...
Detailed Description
Aim of the Study: Validation of FLT-PET as a proliferation marker for colorectal liver metastases, so that the risk of recurrence in patients with resected colorectal liver metastases can be assessed...
Eligibility Criteria
Inclusion
- Colorectal liver metastases deemed resectable on three-phase computed tomography (CT)-scan of the liver
- No evidence of extrahepatic disease on CT chest and abdomen and possible fluorodeoxyglucose (FDG)-PET (if part of surgical work-up)
- No evidence of local recurrence or second primary colorectal tumor on colonoscopy or colonography
- Primary colorectal tumor radically removed
- Informed consent
Exclusion
- Pregnancy
- Recent chemotherapy
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00145665
Start Date
January 1 2005
End Date
December 1 2012
Last Update
September 5 2011
Active Locations (1)
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1
Radboud University
Nijmegen, Gelderland, Netherlands, 6500 HB