Status:
TERMINATED
Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density
Lead Sponsor:
State University of New York - Upstate Medical University
Collaborating Sponsors:
Genentech, Inc.
Conditions:
Osteopenia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this project is to evaluate the hypothesis that bisphosphonate treatment given to growth hormone deficient patients (regardless of current growth hormone replacement therapy status and ...
Detailed Description
Adult patients with Dexa scan (bone scan) z-scores \< -1.0 (meaning low bone density) in at least one site will be selected for randomization. All patients who qualify for randomization will undergo b...
Eligibility Criteria
Inclusion
- Growth hormone deficiency as a complication of treatment for pediatric malignancy
- Dexa (bone densitometry)with z-scores of \< -1.0 in at least one site
Exclusion
- Dexa (bone densitometry)with z-scores \< -1.0 in at least one site
- Subjects \<18 years old
- Pregnant or lactating patients
- Any contraindication for or unwillingness to consider bisphosphonate treatment
- Inability or unwillingness to undergo bone density evaluation
- Other correctable causes of decreased bone mineral density
Key Trial Info
Start Date :
June 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2008
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT00145704
Start Date
June 1 2002
End Date
October 1 2008
Last Update
April 8 2013
Active Locations (1)
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1
Upstate Medical University
Syracuse, New York, United States, 13210