Status:

COMPLETED

Weight Loss and Exercise in Obese, Physically Limited, Older Women and Men

Lead Sponsor:

Washington University School of Medicine

Conditions:

Obesity

Eligibility:

All Genders

65-85 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine the effect of weight loss and exercise on physical function, body fat and muscle mass, bone strength, and quality of life.

Detailed Description

Obesity causes serious medical complications and impairs quality of life. Moreover, in elderly persons, obesity can lead to frailty by exacerbating the decline in strength, endurance, balance and mobi...

Eligibility Criteria

Inclusion

  • Obese (BMI 30 or greater)
  • Elderly (age 65 years or older)
  • Frailty

Exclusion

  • Major chronic disease or any condition that would interfere with exercise or dietary restriction, in which exercise or dietary restriction are contraindicated, or that would interfere with interpretation of results.
  • Examples include cardiopulmonary disease, unstable disease, severe orthopedic or neuromuscular impairments, dementia, history of malignancy during the past 5 years, or current use of bone acting drugs.

Key Trial Info

Start Date :

January 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

107 Patients enrolled

Trial Details

Trial ID

NCT00146107

Start Date

January 1 2005

End Date

December 1 2010

Last Update

April 23 2013

Active Locations (1)

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Washington University School of Medicine

St Louis, Missouri, United States, 63131