Status:
COMPLETED
Intra-Arterial Catheter Directed Therapy for Severe Graft vs. Host Disease (GVHD)
Lead Sponsor:
Hadassah Medical Organization
Conditions:
Graft vs Host Disease
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
PHASE2
Brief Summary
Graft versus host disease (GVHD) is a major complication of allogeneic bone marrow transplantation (BMT), resulting in death in the majority of steroid resistant patients. The study was designed to as...
Detailed Description
Graft versus host disease (GVHD) is the most ominous side effect of allogeneic bone marrow or blood stem cell transplantation (BMT). GVHD causes a severe inflammatory process, which affects primarily ...
Eligibility Criteria
Inclusion
- Recipient of allogeneic stem cell transplantation. AGVHD of liver and or GI tract, grade 2-4. Resistant AGVHD. Signed a written informed consent.
Exclusion
- Not fulfilling any of the inclusion criteria. Active life-threatening infection. Inability to comply with study requirements. Contraindication to arterial catheterization. Has been diagnosed with multi organ failure.
Key Trial Info
Start Date :
December 1 2000
Trial Type :
INTERVENTIONAL
End Date :
August 1 2005
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00146978
Start Date
December 1 2000
End Date
August 1 2005
Last Update
November 7 2006
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hadassah Medical Organization
Jerusalem, Israel, 91120