Status:

COMPLETED

WelChol® and Sulfonylurea in Treating Patients With Type 2 Diabetes

Lead Sponsor:

Daiichi Sankyo

Conditions:

Type 2 Diabetes

Eligibility:

All Genders

18-75 years

Phase:

PHASE3

Brief Summary

The purpose of the study is to see how safe and effective and tolerable the use of colesevelam hydrochloride is for type 2 diabetes when added to sulfonylurea alone or in combination with other anti-d...

Eligibility Criteria

Inclusion

  • Age 18-75 years, inclusive
  • Diagnosed with type 2 diabetes
  • Stable dose of sulfonylurea alone or in combination with other anti-diabetic medications for 90 days
  • Hemoglobin A1c value 7.5% to 9.5%, inclusive
  • C peptide \> 0.5 ng/mL
  • Prescribed ADA diet

Exclusion

  • History of type 1 diabetes or ketoacidosis
  • History of pancreatitis
  • Uncontrolled hypertension
  • Allergy or toxic response to colesevelam or any of its components
  • Serum LDL-C \< 60 mg/dL
  • Serum TG \> 500 mg/dL
  • Body mass index (BMI) \> 45 kg/m2

Key Trial Info

Start Date :

June 1 2004

Trial Type :

INTERVENTIONAL

End Date :

August 1 2006

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00147758

Start Date

June 1 2004

End Date

August 1 2006

Last Update

January 18 2012

Active Locations (47)

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Page 1 of 12 (47 locations)

1

Birmingham, Alabama, United States

2

Tuscumbia, Alabama, United States

3

Little Rock, Arkansas, United States

4

Searcy, Arkansas, United States