Status:
COMPLETED
Diet and Breast Cancer Prevention Trial
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Ontario Ministry of Health and Long Term Care
Canadian Breast Cancer Research Alliance
Conditions:
Breast Cancer
Eligibility:
FEMALE
30-65 years
Phase:
PHASE3
Brief Summary
This randomized controlled trial tests the hypothesis that a reduction in intake of dietary fat will reduce the incidence of breast cancer. Women with more than 50% of the breast occupied by dense tis...
Detailed Description
The long term goal of this trial is to determine if intervention in subjects with extensive mammographic densities (a risk factor for breast cancer) with a low fat-high carbohydrate diet will reduce t...
Eligibility Criteria
Inclusion
- A mammogram with at least 50% of the breast area occupied by radiological signs of density.
- Aged more than 30 years and less than 65 years.
- Body Mass Index \>19 and \<27.
- Resident within easy commuting distance of a participating centre. -
Exclusion
- A previous history of cancer (excluding non-melanomatous skin cancer).
- Pregnant (or planning to be) or breast feeding.
- On a medically prescribed diet for any reason.
- Habitually (ie. 4 or more times per week) eats more than one meal a day in a restaurant.
- Previous mammoplasty, either reduction or augmentation.
- Previous or present treatment for the reduction of blood lipids.
- Proposed breast biopsy as a result of the initial clinical and/or mammographic examination, until such time as the biopsy has been carried out and is known to be benign
Key Trial Info
Start Date :
January 1 1988
Trial Type :
INTERVENTIONAL
End Date :
December 1 2005
Estimated Enrollment :
4695 Patients enrolled
Trial Details
Trial ID
NCT00148057
Start Date
January 1 1988
End Date
December 1 2005
Last Update
September 7 2005
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Health Network
Toronto, Ontario, Canada, M5G 2M9