Status:
COMPLETED
Energy Homeostasis Under Treatment With Atypical Antipsychotics
Lead Sponsor:
Charite University, Berlin, Germany
Conditions:
Schizophrenia
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to evaluate the effects of different atypical antipsychotics on weight changes, energy homeostasis, metabolism, energy intake as well as activity. Patients with schizophr...
Eligibility Criteria
Inclusion
- Diagnosis of schizophrenia or related disorders(DSM-IV)
- Indication for long-term treatment with antipsychotics
- BMI between 20 to 30
- Weight changes less than 3kg in the last 3 months before inclusion
- Informed consent
Exclusion
- Psychiatric comorbidity
- Depot antipsychotic in the last 2 months
- Antipsychotics in the last 2 weeks
- Treatment with olanzapine, clozapine or ziprasidone in teh last 3 months
- Treatment with drugs, that may lead to weight changes
- Significant endocrine, neurological, cardiovascular, hepatic, renal, metabolic, or other medical diseases or any clinically relevant abnormalities in laboratory tests
- Female subjects during pregnancy and breastfeeding
- Female subjects within childbearing years who were not using adequate birth control
- Patients who are judged by the investigator to be at serious suicide risk
Key Trial Info
Start Date :
March 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2007
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00148564
Start Date
March 1 2004
End Date
June 1 2007
Last Update
September 29 2008
Active Locations (1)
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1
Charité Universitaetsmedizin Berlin; Campus Charité Mitte; Dept. for Psychiatry and Psychotherapy
Berlin, Germany, 10117