Status:
UNKNOWN
Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.
Lead Sponsor:
University Hospital, Geneva
Conditions:
Wound Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The aim of this study is to determine whether vancomycin with cefazoline is superior to vancomycin with placebo in preventing gastrostomy-related wound infection in carriers of methicillin-resistant s...
Detailed Description
Percutaneous endoscopic gastrostomy (PEG) provides an enteral route for long-term nutrition in patients unable to swallow. Peristomal wound infection occurs in 5 - 30 % of patients. Systematic antibio...
Eligibility Criteria
Inclusion
- PEG insertion in a patient with a swab positive for MRSA during the 4 weeks preceding PEG insertion
Exclusion
- Age \< 18 years
- No informed consent obtained either from the patient or from his legal representative
- Contraindication to the administration of cefazolin or of vancomycin
- Systemic administration of antibiotics effective against MRSA during the week prior to the procedure
- Technique of PEG insertion different from the standard pull technique proposed by the physician in charge and the gastroenterologist
- Patients requiring antibiotic prophylaxis of endocarditis
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT00150852
Start Date
September 1 2004
Last Update
December 29 2005
Active Locations (3)
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1
Centre Hospitalier Universitaire (CHU)
Grenoble, France, 38000
2
Division of Gastroenterology, University Hospital
Geneva, Canton of Geneva, Switzerland, 1211
3
Centre Hospitalier Universitaire Vaudois
Lausanne, Canton of Vaud, Switzerland, 1011