Status:
COMPLETED
The Use of an Inhaled Salt Solution to Treat Viral Lung Infections in Infants.
Lead Sponsor:
Sheikh Khalifa Medical City
Conditions:
Bronchiolitis
Eligibility:
All Genders
Up to 18 years
Phase:
PHASE2
PHASE3
Brief Summary
Bronchiolitis is a common viral lung infection in infants. Standard treatment often includes the use of inhaled medications which are usually first mixed with a standard salt solution. Inhalation of a...
Detailed Description
Bronchiolitis is a common illness in infants and is associated with a significant morbidity. Standard therapy is controversial and largely ineffective; care is mostly supportive although nebulized med...
Eligibility Criteria
Inclusion
- Corrected age maximum 18 months, plus
- History of preceding viral upper respiratory tract infection, plus
- Presence of wheezing and/or crackles on auscultation, plus
- Respiratory Distress Assessment Instrument (RDAI) score of 4 or greater, or oxygen saturation of 93% or less in room air, plus
- Admitted to hospital
Exclusion
- Prior history of wheezing, or
- History of chronic cardiopulmonary disease or immunodeficiency, or
- Critical illness at presentation requiring admission to ICU, or
- Use of nebulized hypertonic saline within previous 12 hours, or
- Prematurity (gestational age 34 weeks or less).
Key Trial Info
Start Date :
November 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00151905
Start Date
November 1 2003
End Date
September 1 2006
Last Update
May 7 2007
Active Locations (3)
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1
Victoria General Hospital
Victoria, British Columbia, Canada
2
Kingston General Hospital
Kingston, Ontario, Canada, K7L 2V7
3
Sheikh Khalifa Medical City
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 51900