Status:

COMPLETED

Safety & Tolerability of MTS in Children Aged 6-12 Diagnosed With ADHD & Previously Treated With Extended-Release Methylphenidate Therapy

Lead Sponsor:

Noven Therapeutics

Collaborating Sponsors:

Noven Pharmaceuticals, Inc.

Conditions:

Attention Deficit Disorder With Hyperactivity

Eligibility:

All Genders

6-12 years

Phase:

PHASE3

Brief Summary

This study will assess the safety and tolerability of MTS while attempting to establish the appropriate starting dose for subjects previously on an existing long-acting methylphenidate product.

Detailed Description

Attention-Deficit/Hyperactivity Disorder (ADHD) is a psychiatric disorder characterized by 3 main symptoms: inattention, hyperactivity and impulsivity. This study will assess the safety and tolerabili...

Eligibility Criteria

Inclusion

  • Subject must have a primary diagnosis of ADHD
  • Subject must be adequately controlled on a stable dose of one of the following medications for a 30 day period: Ritalin LA(r), Concerta(r), or Metadate DC(r), not to exceed 54 mg per day
  • Females of childbearing potential must have a negative serum beta Human Chorionic Gonadotropin pregnancy test

Exclusion

  • A history of mental retardation that would indicate that the subject is not functioning at an age appropriate level intellectually
  • A recent history of suspected substance abuse or dependence disorder
  • Subject is taking Strattera
  • Clinical signs and symptoms of skin irritation or hyper/hypopigmentation at the potential application sites

Key Trial Info

Start Date :

June 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2006

Estimated Enrollment :

175 Patients enrolled

Trial Details

Trial ID

NCT00151983

Start Date

June 1 2005

End Date

July 1 2006

Last Update

July 9 2015

Active Locations (18)

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Page 1 of 5 (18 locations)

1

Meadowbrook Research, Inc.

Scottsdale, Arizona, United States

2

Psychiatric Centers at San Diego

San Marcos, California, United States

3

Alpine Clinical Research Center

Boulder, Colorado, United States

4

Miami Research Associates, Inc.

Miami, Florida, United States