Status:
COMPLETED
Salt Reduction on Blood Pressure and Cardiovascular Organ Damage
Lead Sponsor:
St George's, University of London
Conditions:
Hypertension
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to determine the effect of a modest reduction in salt intake on blood pressure in white, black and Asian individuals with hypertension or prehypertension, and also to dete...
Detailed Description
The average salt intake for adults in the UK is approximately 10-12 g/day. The current recommendations are to reduce salt intake to 5-6 g/day or less. Many randomised trials have shown that this reduc...
Eligibility Criteria
Inclusion
- Patients with untreated essential hypertension or prehypertension (sitting systolic blood pressure between 120 and 170 mmHg and/or sitting diastolic blood pressure between 80 and 105 mmHg)
- Age 18 - 75 years.
Exclusion
- Individuals younger than 18 or older than 75 years
- Individuals with severe hypertension i.e. blood pressure \> 170/105 mmHg
- Individuals with any secondary cause of hypertension
- Individuals with impaired renal function with plasma creatinine greater than 150 umol/L
- Individuals with diabetes mellitus
- Individuals with malignancy or liver disease
- Individuals with ischaemic heart disease or heart failure
- Females who are pregnant or breast feeding or on the oral contraceptive pill.
Key Trial Info
Start Date :
April 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2007
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT00152074
Start Date
April 1 2004
End Date
December 1 2007
Last Update
June 9 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
St. George's University of London,
London, United Kingdom, SW17 0RE