Status:
COMPLETED
Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome
Lead Sponsor:
St. Jude Children's Research Hospital
Conditions:
Severe Combined Immunodeficiency
Eligibility:
All Genders
Up to 2 years
Phase:
PHASE1
Brief Summary
Treatment for severe combined immunodeficiency (SCID) is a medical emergency. A stem cell transplant (immature blood cells that can make other blood cells) from a (MSD) matched sibling donor (brother ...
Eligibility Criteria
Inclusion
- Patient with confirmed severe combined immunodeficiency
- Two years of age or younger
- A suitable matched sibling donor is not available
Exclusion
- An available matched sibling donor or a confirmed matched unrelated donor
- Patients with DiGeorge syndrome, Zap70, MHC Class II deficiency, or cartilage-hair hypoplasia
- Patients with a Lansky performance score of less than 10, evidence of HIV or a congenital rubella infection or a documented neoplasm
- Patients in whom it is not possible to perform a peripheral blood cell harvest on a haploidentical family member
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2007
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT00152100
Start Date
February 1 2004
End Date
August 1 2007
Last Update
May 20 2009
Active Locations (1)
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1
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105