Status:
COMPLETED
High Dose Candesartan Versus Quinapril for Restenosis Prophylaxis After Stent Angioplasty
Lead Sponsor:
Technische Universität Dresden
Conditions:
Arterial Occlusive Diseases
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The study is designed to test the hypothesis that high dose candesartan treatment compared to quinapril is able to reduce intima hyperproliferation and the restenosis rate after stent angioplasty in p...
Detailed Description
Patients are randomly assigned to treatment with either candesartan 32 mg/d or Quinapril 20 mg/d before the angioplasty. Walking distance, intima media thickness and crurobrachial pressure ratios are ...
Eligibility Criteria
Inclusion
- male and female
- peripheral occlusive arterial disease Stad IIb Fontaine classification
Exclusion
- patients with lesions not available for PTA
- renal insufficiency
- patients on calcium-antagonists
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
End Date :
July 1 2006
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00154050
Start Date
May 1 2004
End Date
July 1 2006
Last Update
September 12 2006
Active Locations (1)
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1
Chemnitz Hospital, Dept. of Internal Medicine I
Chemnitz, Germany, 09313