Status:
UNKNOWN
Genomewide Screening of Pathological Myopia
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Pathological Myopia
Eligibility:
All Genders
Brief Summary
The purpose of this study is to evaluate the possible candidate gene of pathological myopia
Detailed Description
High myopia (pathological myopia) is caused by excessive axial elongation that primarily involves the ora-equatorial area and the posterior pole. Peripheral fundus changes and posterior staphyloma for...
Eligibility Criteria
Inclusion
- They are unrelated Chinese subjects with high myopia ≦-6.00D. The diagnosis of myopia is determined by the refractive error. Anisometropic individuals, with a refractive error of ≦-6.00 D for one eye and ≦-6.00 D for the other eye, with at least a 2-D difference between the two eyes, are considered unaffected.
Exclusion
- Individuals are excluded if there is known ocular disease or insult that could predispose to myopia, such as retinopathy of prematurity or early-age media opacification, or if they had a known genetic disease associated with myopia, such as Stickler or Marfan syndrome.
Key Trial Info
Start Date :
August 1 2002
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2010
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00155753
Start Date
August 1 2002
End Date
August 1 2010
Last Update
June 9 2010
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100