Status:

UNKNOWN

Immunologic Factors in Reflux Esophagitis and Barrett's Esophagus

Lead Sponsor:

National Taiwan University Hospital

Conditions:

Reflux Esophagitis

Hiatal Hernia

Eligibility:

All Genders

18-80 years

Brief Summary

By using combination of the expression of COX-2 and NOS and immunologic reaction in the esophagus with manometry of LES and cruel diaphragm and 24 hr esophageal pH monitoring to investigate the mechan...

Detailed Description

It has been commonly accepted that there is considerable geographic variation in the prevalence of gastroesophageal reflux disease (GERD) and much less prevalent in Asia. However, a tendency of increa...

Eligibility Criteria

Inclusion

  • age between 18-80
  • endoscopy diagnosed esophagitis
  • GERD questionnaire screened nonerosive reflux disease

Exclusion

  • A history of esophageal, gastric or abdominal surgery.
  • Gastric or esophageal cancer.
  • Esophageal varices.

Key Trial Info

Start Date :

February 1 2004

Trial Type :

OBSERVATIONAL

End Date :

December 1 2006

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT00155805

Start Date

February 1 2004

End Date

December 1 2006

Last Update

November 28 2005

Active Locations (1)

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1

National Taiwan University Hospital

Taipei, Taiwan, 10016