Status:

COMPLETED

Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids

Lead Sponsor:

Abbott

Conditions:

Leiomyoma

Menorrhagia

Eligibility:

FEMALE

18+ years

Phase:

PHASE3

Brief Summary

The objective of this study is to determine the long-term safety of asoprisnil in women with abnormal uterine bleeding associated with uterine fibroids.

Detailed Description

No medical therapy is currently available for the long-term treatment of abnormal uterine bleeding associated with uterine fibroids in women and many women must resort to surgery for relief. The objec...

Eligibility Criteria

Inclusion

  • Women who have completed 12 months of treatment in study M01-390 or study M01-394 and their Visit 12 procedures, respectively
  • Otherwise in good health
  • Premenopausal based on Estrogen and FSH levels
  • Agrees to use of double barrier method of contraception
  • Adequate endometrial biopsy with no significant histological disorder

Exclusion

  • Any abnormal lab or procedure result(s) the study-doctor considers important
  • Significant gynecological disorder such as confirmed endometrial polyp
  • Hemoglobin \< 8.0 g/dL
  • History of a blood-clotting disorder
  • Any prior surgical and/or invasive procedure(s) for uterine fibroids that resulted in either a cure or made the symptoms go away.

Key Trial Info

Start Date :

September 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2007

Estimated Enrollment :

523 Patients enrolled

Trial Details

Trial ID

NCT00156195

Start Date

September 1 2003

End Date

January 1 2007

Last Update

May 29 2008

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