Status:
COMPLETED
Cognitive Behavioral Therapy for Depression Relapse Prevention in Children and Adolescents
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Depression
Eligibility:
All Genders
11-18 years
Phase:
NA
Brief Summary
This study will determine the effectiveness of cognitive behavioral therapy in preventing a relapse of depressive symptoms in children.
Detailed Description
Depression is a chronic and episodic condition that may have devastating effects on social and emotional functioning, particularly in the pediatric population. While approximately 90% of children even...
Eligibility Criteria
Inclusion
- Diagnosis of nonpsychotic major depressive disorder at least 4 weeks prior to study entry
- Clinical Global Impression severity score of 4 or greater
- Children's Depression Rating Scale score of 40 or greater
- Currently attending school
- Willing and able to use acceptable methods of contraception, if applicable
- In good general health
- Parent or guardian willing to provide informed consent, if applicable
Exclusion
- History of psychotic disorders
- Alcohol or substance abuse or dependence within 6 months prior to study entry
- History of anorexia nervosa or bulimia
- Chronic medical illness requiring regular medication
- Current use of medication with psychotropic effects
- First-degree relatives (e.g., mother, father, sister, brother) with bipolar I disorder
- At risk for suicide
- Failure of a previous adequate treatment with fluoxetine (defined as at least 40 mg/day for 4 weeks)
- IQ less than 80
- Pregnancy or breastfeeding
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT00158301
Start Date
September 1 2004
End Date
February 1 2008
Last Update
November 8 2013
Active Locations (1)
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1
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390