Status:
COMPLETED
Reducing the Weight of Overweight Schizophrenia Patients
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Schizophrenia
Obesity
Eligibility:
All Genders
14-60 years
Phase:
NA
Brief Summary
This study will determine the effectiveness of a group-based behavioral program for weight reduction in overweight and obese schizophrenia patients.
Detailed Description
Researchers have found a link between schizophrenia, high blood pressure, and insulin resistance; this link puts people with schizophrenia at an increased risk for diabetes and obesity. Weight reducti...
Eligibility Criteria
Inclusion
- Diagnosis of schizophrenia or schizoaffective disorder
- Body mass index (BMI) greater than 27
- Stable on antipsychotic drug regimen for at least 1 month prior to study entry
- Parent or guardian willing to provide informed consent, if applicable
- Positive and negative syndrome scale score less than 90
- Willing to use acceptable methods of contraception during the study
Exclusion
- Medical contraindication for participating in a weight reduction/exercise program
- Mental retardation
- Current enrollment in another weight management program
- Current use of weight reduction medication
- Unstable cardiovascular or thyroid disease
- Active or end-stage renal disease
- Psychiatric hospitalization within 1 month prior to study entry
- Current use of more than one anti-psychotic medication
- Pregnancy or breastfeeding
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2018
Estimated Enrollment :
261 Patients enrolled
Trial Details
Trial ID
NCT00158366
Start Date
May 1 2004
End Date
July 1 2018
Last Update
August 22 2018
Active Locations (1)
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1
Western Psychiatric Institute and Clinic of University of Pennsylvania Medical Center
Pittsburgh, Pennsylvania, United States, 15213