Status:
COMPLETED
Eight Week Primaquine Regimen for the Treatment of Vivax Malaria
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
HealthNet TPO
Conditions:
Malaria
Vivax Malaria
Eligibility:
All Genders
3-70 years
Phase:
PHASE3
Brief Summary
Plasmodium vivax represents a major health problem throughout the tropics. Outside Africa it accounts for over 50% of cases, affecting an estimated 70-80 million people per year. A substantial proport...
Detailed Description
Old evidence suggests that successful PQ therapy is not a function of the length of the course of treatment, nor the circulating concentration of the drug, but of the total dosage administered. The sa...
Eligibility Criteria
Inclusion
- Patients diagnosed with P. vivax parasitaemia
- Patients over 3 years
- Patients with G6PD deficiency to a safety trial
- Patients without G6PD deficiency to all other groups.
Exclusion
- Children under the age of three
- Pregnant / breast feeding women
- Patients with severe clinical anaemia \[Hb\<7g/dl\]
- Patients with P. falciparum
- Patients unavailable for the duration of study.
- Patients who have taken antimalarial drugs in the 2 weeks prior to consultation.
- Patients with concomitant infections or whose general health is considered too poor.
Key Trial Info
Start Date :
April 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2007
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00158587
Start Date
April 1 2004
End Date
March 1 2007
Last Update
January 12 2017
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