Status:

COMPLETED

A Comparison of One Versus Two Doses of Influenza Vaccine in Children 5-8 Years of Age

Lead Sponsor:

Kaiser Permanente

Collaborating Sponsors:

Centers for Disease Control and Prevention

Conditions:

Influenza

Eligibility:

All Genders

5-8 years

Phase:

NA

Brief Summary

The purpose of the study was to find out if children 5 through 8 years of age who are getting influenza vaccine for the first time should get one or two doses.

Detailed Description

Currently, two doses of influenza vaccine are recommended for children younger than 9 years receiving influenza vaccine for the first time. While the scientific support for 2 doses of vaccine in infan...

Eligibility Criteria

Inclusion

  • Immunocompetent children who are at least 5 and no more than 8 years of age on the date of the first vaccination.
  • Parents able to give informed consent and child available for all study visits.
  • Family able to understand and comply with planned study procedures.
  • Family must have telephone accessibility.

Exclusion

  • Previous receipt of influenza vaccine of any kind (shot or nasal spray).
  • Active cancer or blood system abnormalities such as leukemia.
  • Immunocompromising illnesses or current receipt of immunosuppressive agents
  • Allergy to eggs or egg protein, or to gentamicin (an antibiotic that is present in trace amounts in the vaccine).
  • Any acute or chronic condition that (in the opinion of the investigator) would render vaccination unsafe or would interfere with the evaluation of responses.
  • Temporary

Key Trial Info

Start Date :

August 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2004

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT00158665

Start Date

August 1 2004

End Date

December 1 2004

Last Update

October 13 2017

Active Locations (1)

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Group Health Research Institute

Seattle, Washington, United States, 98101