Status:

COMPLETED

Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Radiculopathy

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Trial will evaluate the efficacy and safety of pregabalin in the treatment of subjects with neuropathic pain associated with lumbo-sacral radiculopathy.

Eligibility Criteria

Inclusion

  • Pain consistent with a diagnosis of chronic lumbo-sacral radiculopathy due to spinal stenosis or disk herniation.
  • Radicular pain must be present for at least 3 months and pain stable for at least 4 weeks.

Exclusion

  • Surgery for lumbo-sacral radiculopathy within previous 6 months and/or more than one previous spinal surgery for pain-radiculopathy.
  • Epidural injection for lumbo-sacral radiculopathy within previous 6 weeks and/or anticipated need for treatment with opioid analgesics, anti-epileptic medications or tricyclic antidepressants to alleviate pain due to lumbo-sacral radiculopathy during the course of the study.

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2007

Estimated Enrollment :

276 Patients enrolled

Trial Details

Trial ID

NCT00159705

Start Date

April 1 2005

End Date

June 1 2007

Last Update

January 25 2021

Active Locations (52)

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Page 1 of 13 (52 locations)

1

Pfizer Investigational Site

Phoenix, Arizona, United States, 85023

2

Pfizer Investigational Site

Denver, Colorado, United States, 80218

3

Pfizer Investigational Site

Plantation, Florida, United States, 33324

4

Pfizer Investigational Site

Chicago, Illinois, United States, 60612