Status:
TERMINATED
Cleansing of Suction Blood in Cardiac Surgery for Reduced Inflammatory Response
Lead Sponsor:
Rigshospitalet, Denmark
Collaborating Sponsors:
Danish Heart Foundation
Copenhagen Hospital Corporation
Conditions:
Systemic Inflammatory Response Syndrome
Coronary Arteriosclerosis
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Cardiac surgery using heart and lung machine produces an inflammatory reaction in the body. This leads in few percent of cases to heart, lung, and kidney disturbances that potentially causes death. Wh...
Detailed Description
Introduction Cardiopulmonary bypass (CPB) during cardiac surgery induces in all patients a systemic inflammatory response syndrome (SIRS) that is more pronounced than for other surgical procedures. D...
Eligibility Criteria
Inclusion
- Oral and written informed consent.
- No limits regarding age or ejection fraction.
Exclusion
- Off-pump coronary artery bypass grafting
- Redo CABG
- Current infection
- Antibiotic treatment
- S-creatinin \> 200 micromol/L
- Antiinflammatory / immuno-modulating treatment: Steroids, immunosuppressive or -stimulating agents (NSAIDs and ASA allowed)
- Liver disease
- Immune disease
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2004
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00159926
Start Date
January 1 2003
End Date
February 1 2004
Last Update
January 14 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Cardiothoracic Surgery, Rigshospitalet
Copenhagen, Denmark, 2100