Status:
COMPLETED
Genetic Liability in the Brain Morphology of Attention Deficit Hyperactivity Disorder
Lead Sponsor:
UMC Utrecht
Collaborating Sponsors:
The Dutch Brain Foundation
Conditions:
Attention Deficit Hyperactivity Disorder
Eligibility:
MALE
7-18 years
Brief Summary
Attention Deficit Hyperactivity Disorder (ADHD) is a heritable psychiatric disorder with onset in childhood. Twin and adoption studies indicate that additive genetic factors explain up to 80% of the v...
Eligibility Criteria
Inclusion
- age 7 - 18 years.
- Inclusion criteria for patients
- DSM-IV (APA, 1994) diagnosis of ADHD (combined subtype), according to DISC interview
- scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)
- one brother who meets the inclusion criteria for siblings
- Inclusion criteria for siblings
- no DSM-IV (APA,1994) diagnosis for ADHD or another disruptive disorder (ODD or CD), according to DISC interview
- no scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)
- Inclusion criteria for controls
- no DSM-IV (APA, 1994) diagnosis, according to DISC interview
- no scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)
Exclusion
- IQ \< 70
- illness of the cardiovascular, the endocrine, the pulmonal or the gastrointestinal system
- the presence of metal objects in or around the body (pacemaker, dental braces)
Key Trial Info
Start Date :
October 1 1999
Trial Type :
OBSERVATIONAL
End Date :
December 1 2002
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00161161
Start Date
October 1 1999
End Date
December 1 2002
Last Update
December 30 2005
Active Locations (1)
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1
UMC Utrecht
Utrecht, Netherlands, 3584CX