Status:
COMPLETED
Symptomatic Gastroesophageal Reflux Disease: Double Blind Randomized Controlled Study of On-demand Therapy Versus Maintenance Therapy
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Gastroesophageal Reflux Disease
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
Maintenance treatment with proton pump inhibitor (PPI) is the most widely recommended modality of treatment for long-term management of gastroesophageal reflux disease (GERD). Yet in clinical practice...
Eligibility Criteria
Inclusion
- Weekly symptoms of heartburn or acid regurgitation of moderate severity as predominant complaint for at least 6 months
Exclusion
- Erosive esophagitis
- Concomitant peptic ulcer disease
- Use of NSAID in recent 4 weeks (Low dose aspirin \< 300 mg is allowed)
- Pregnant or lactating female
- Illiterate patient (who cannot administer questionnaire)
- Known hypersensitivity to PPI
Key Trial Info
Start Date :
May 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2008
Estimated Enrollment :
244 Patients enrolled
Trial Details
Trial ID
NCT00164840
Start Date
May 1 2003
End Date
November 1 2008
Last Update
March 30 2010
Active Locations (1)
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1
Endoscopy Centre, Prince of Wales Hospital
Hong Kong, China