Status:

COMPLETED

Treatment of Acute Lymphoblastic Leukemia in Children

Lead Sponsor:

Dana-Farber Cancer Institute

Collaborating Sponsors:

Boston Children's Hospital

University of Rochester

Conditions:

Acute Lymphoblastic Leukemia

Eligibility:

All Genders

1-18 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to reduce the side-effects from anti-leukemia therapy. The therapy in this study is based upon treatment information learned from prior clinical research programs as well ...

Detailed Description

* Children with acute lymphoblastic leukemia are treated somewhat differently depending on the relative risk of the leukemia recurring. Patients will be separated into "Standard Risk" and "High Risk"....

Eligibility Criteria

Inclusion

  • Acute lymphoblastic leukemia excluding known mature B-cell ALL by the presence of any of the following: surface immunoglobulin, L3 morphology, t(8;14) (q24;q32), t(8;22) or t(2;8)
  • Age \> 12 months but less than 18 years

Exclusion

  • Prior therapy except, 1 week of steroids, or emergent radiation therapy to the mediastinum
  • Known HIV positive

Key Trial Info

Start Date :

September 1 2000

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2011

Estimated Enrollment :

498 Patients enrolled

Trial Details

Trial ID

NCT00165178

Start Date

September 1 2000

End Date

May 1 2011

Last Update

April 25 2013

Active Locations (1)

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1

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02115