Status:

WITHDRAWN

Thiopurine Methyltransferase Polymorphisms Evaluation

Lead Sponsor:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Cancer

Eligibility:

All Genders

Up to 18 years

Brief Summary

The purpose of the study is to determine the frequency of allelic variants in TPMT in the Hispanic population and to compare the frequency in the Hispanic population with the Caucasian Population.

Detailed Description

Relatively few studies have been performed evaluating the variant allele frequencies in Spanish populations. To date, no studies evaluating the TPMT variant allele frequency in the Hispanic population...

Eligibility Criteria

Inclusion

  • All Hispanic children and adolescents diagnosed and treated at Texas Children's Cancer Center within the last 5 years for malignant diseases/cancer and non-malignant hematological disorders that necessitate chemotherapy
  • All Hispanic children and adolescents who will be treated at Texas Children's Center for malignant diseases/cancer and non-malignant hematological disorders that will necessitate chemotherapy.

Exclusion

  • Any child or adolescent registering at Texas Children's Cancer Center and not requiring any form of therapy.

Key Trial Info

Start Date :

February 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00166647

Start Date

February 1 2004

Last Update

January 11 2013

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Baylor College of Medicine, Texas Children's Hospital

Houston, Texas, United States, 77030