Status:
TERMINATED
Campath-1H Induction to Allow Steroid Free Immunosuppression in Pediatric Renal Transplantation
Lead Sponsor:
University of Wisconsin, Madison
Conditions:
Disorder Related to Renal Transplantation
Eligibility:
All Genders
18-18 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine whether Campath-1H induction and the associated lymphocyte depletion will permit long-term rejection-free renal allograft survival in the absence of ongoing c...
Eligibility Criteria
Inclusion
- Participants must be a single-organ recipient (kidney only)
- Participants who are receiving their first living donor or deceased donor transplant
Exclusion
- Participants who are recipients of HLA-identical living-donor renal transplants
- Participants with a PRA value \> 10% within 30 days prior to the transplant
- Participants who have received a multi-organ transplant
- Participants who are who are positive for hepatitis C, hepatitis B surface antigen or HIV
- Participants who have received an investigational drug within 6 weeks of study entry
- Participants who have a previous history of, or who currently have, malignancies and/or lymphoma
- Participants who have received corticosteroids within three months of transplantation
- Participants who are 3rd transplant recipients
- Female participants who are pregnant or lactating. Fertile female participants who are sexually active must agree to use an acceptable method of birth control during the study
Key Trial Info
Start Date :
June 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT00167661
Start Date
June 1 2004
End Date
May 1 2012
Last Update
September 21 2020
Active Locations (1)
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1
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792