Status:
UNKNOWN
The Role of SNP of ECM and MMP on the Development of Pathological High Myopia
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Myopia
Eligibility:
All Genders
Brief Summary
To study the clinical characteristics and inheritance of pathological myopia in Taiwanese patients.
Detailed Description
High myopia (pathological myopia) is caused by excessive axial elongation that primarily involves the ora-equatorial area and the posterior pole. Pathological myopia often accompanied by glaucoma, cat...
Eligibility Criteria
Inclusion
- They are unrelated Chinese subjects with high myopia ≦-6.00D. The diagnosis of myopia is determined by the refractive error. Anisometropic individuals, with a refractive error of ≦-6.00 D for one eye and ≦-6.00 D for the other eye, with at least a 2-D difference between the two eyes, are considered unaffected
Exclusion
- Individuals are excluded if there is known ocular disease or insult that could predispose to myopia, such as retinopathy of prematurity or early-age media opacification, or if they had a known genetic disease associated with myopia, such as Stickler or Marfan syndrome.
Key Trial Info
Start Date :
June 1 2005
Trial Type :
OBSERVATIONAL
End Date :
January 1 2006
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00172952
Start Date
June 1 2005
End Date
January 1 2006
Last Update
September 15 2005
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan