Status:
UNKNOWN
The Role of Insulin Resistance in PCOS
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Polycystic Ovary Syndrome
Insulin Resistance
Eligibility:
FEMALE
12-50 years
Brief Summary
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insulin resistance...
Detailed Description
Because of the menstrual irregularity and the hirsutism/acne caused by hyperandrogenism, the treatment of choice for PCOS in young teenagers is to given the oral contraceptive; however, such oral cont...
Eligibility Criteria
Inclusion
- Criteria for the definition of PCOS: (2 out of 3 in the following) Oligomenorrhea / chronic anovulation, defined as less than eight cycles of spontaneous menstrual period in one year.
- Clinical and /or biochemical signs of hyperandrogenism Polycystic ovaries Exclusion of other aetiologies, such as congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome
Exclusion
- ever received hormone therapy in the past 6 months, having pregnancy in the past 6 months, having acute illness found in the past 3 months, or having systemic diseases including autoimmune disease, malignancy, hepatic, renal or CVS disease, and ever received chemotherapy or immunosuppressive agents.
Key Trial Info
Start Date :
October 1 2004
Trial Type :
OBSERVATIONAL
End Date :
August 1 2005
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT00173043
Start Date
October 1 2004
End Date
August 1 2005
Last Update
November 24 2005
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100