Status:
UNKNOWN
Screening for CRC Using a Mixed Strategy of Sigmoidoscopy and Colonoscopy in Average-Risk Population According to Age
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Colorectal Cancer
Eligibility:
All Genders
50+ years
Brief Summary
BACKGROUND: Primary screening with sigmoidoscopy would miss a substantial proportion of advanced proximal neoplasia (APN), but screening with universal colonoscopy is costly. The aim of this study is ...
Detailed Description
Because the prevalence of proximal colon cancer and APN was higher in older patients15, a greater proportion of advanced colonic neoplasia or cancer would be missed if colonoscopy was not performed fo...
Eligibility Criteria
Inclusion
- Only asymptomatic ethnic Chinese subjects aged 50 years or older who underwent total colonoscopy were included in this study
Exclusion
- Persons with symptoms indicative of colorectal cancer, such as hematochezia, body weight loss, development of persistent abdominal pain or rectal pain, and a change in bowel habit, were excluded from this study. Other exclusion criteria were: (1) past history of CRC, colon polyps, or inflammatory bowel disease; (2) a history of screening tests, including FOBT, sigmoidoscopy, colonoscopy, or barium studies within 5 years; (3) any first degree relative(s) with colon cancer; (4) criteria for hereditary nonpolyposis colorectal cancer, familial adenomatous polyposis, or other polyposis syndrome; (5) obvious anemia with hemoglobin level less than 10g/dl; (6) incomplete examination of entire colon, including poor colon preparation and failure to reach cecum.
Key Trial Info
Start Date :
June 1 2003
Trial Type :
OBSERVATIONAL
End Date :
July 1 2004
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT00173277
Start Date
June 1 2003
End Date
July 1 2004
Last Update
September 15 2005
Active Locations (1)
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1
Departments of Internal Medicine, Medicine National Taiwan University Hospital,
Taipei, Taiwan, 100