Status:

COMPLETED

A Methodological Open Label Cross-Over Controlled Study To Assess The Effect Of Drugs On Ventricular Repolarization and QT Interval At Fixed Heart Rate Under Autonomic Blockade

Lead Sponsor:

Pfizer

Conditions:

Patients With Pace Makers But no Evidence of Ischemic Heart Disease

Eligibility:

All Genders

18-75 years

Phase:

PHASE1

Brief Summary

To assess the effects of GTN on QT and QTc in subjects with And without atrial pacing. This will be done with and without autonomic blockade at two different pacing rates. Moxifloxacin effect on QT an...

Eligibility Criteria

Inclusion

  • Patients with pace-makers but otherwise normal ventricular function

Exclusion

  • Nitrates, beta blockers

Key Trial Info

Start Date :

March 1 2005

Trial Type :

INTERVENTIONAL

End Date :

June 1 2006

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT00174512

Start Date

March 1 2005

End Date

June 1 2006

Last Update

November 8 2006

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Pfizer Investigational Site

Bruxelles (Brussels), Belgium

2

Pfizer Investigational Site

Glasgow, Scotland, United Kingdom

3

Pfizer Investigational Site

Leicester, United Kingdom

4

Pfizer Investigational Site

Liverpool, United Kingdom