Status:

COMPLETED

Validation Study of Physical Measurement of Tophi

Lead Sponsor:

Takeda

Conditions:

Gout

Eligibility:

All Genders

18-85 years

Brief Summary

The purpose of this study is to determine the inter- and intra-rater reproducibility of direct physical measurement of tophus nodules in subjects with gout.

Detailed Description

Gout is a chronic urate crystal deposition disorder. Left untreated, gout may result in progressive disease characterized by joint and bone destruction from tophaceous deposits and renal impairment du...

Eligibility Criteria

Inclusion

  • Must have at least 1 palpable gouty tophus nodule in the foot/ankle, hand/wrist, or elbow, confirmed as gouty by prior diagnosis according to ACR criteria.
  • The tophus must be solid, round, non-tender, intact, and larger than 10mm in both length and width.
  • Joints nearest and immediately adjacent to the selected tophus must not be acutely inflamed.
  • Must be on stable treatment for gout with no medication changes in the past 30 days.

Exclusion

  • Must be able to return to the clinical site within 10 days.
  • Must not have allergy to ink.

Key Trial Info

Start Date :

November 1 2002

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2003

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT00175006

Start Date

November 1 2002

End Date

January 1 2003

Last Update

July 27 2010

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