Status:

COMPLETED

Levetiracetam in the Treatment of Neuroleptic-induced Tardive Dyskinesia

Lead Sponsor:

UCB Pharma

Conditions:

Dyskinesia, Medication-induced

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

An 8-week study to examine safety and efficacy of levetiracetam in patients with neuroleptic-induced tardive dyskinesia

Eligibility Criteria

Inclusion

  • Subjects between ages 18 and 80 years
  • Subjects must have a diagnosis of stable axis I psychiatric disorder at least 6 months prior to screening
  • Subjects must have a stable neuroleptic-induced tardive dyskinesia at least 1 month prior to screening and meet tardive dyskinesia severity criteria
  • Subjects must have used antipsychotics for at least 6 cumulative months, and, be on a stable dose for 1 month prior to screening

Exclusion

  • Presence of any axis II condition within 6 months prior to screening
  • Huntington´s disease, idiopathic dystonia, Wilson´s disease, Sydenham´s chorea, thyroid dysfunction, spontaneous dyskinesia
  • Start of drugs-other than neuroleptics- that can cause dyskinesia
  • Presence of additional major disease such as cardiac, renal or hepatic dysfunction or terminal illness

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2005

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00175955

Start Date

May 1 2005

End Date

December 1 2005

Last Update

December 6 2013

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Antwerp, Belgium

2

Bourgois, Belgium

3

Gonce, Belgium

4

Hulselmans, Belgium