Status:
UNKNOWN
Impact of Exercise Training on Endothelial Function in CAD
Lead Sponsor:
University of Leipzig
Conditions:
Coronary Artery Disease
Eligibility:
MALE
18-75 years
Phase:
PHASE2
Brief Summary
Bradykinin has been identified to contribute to the release of nitric oxide (NO), prostacyclin, and EDHF through activation of specific bradykinin 2 (B2) receptors, which is finally promoting a vasodi...
Detailed Description
A total of 20 patients with stable coronary artery disease are prospectively randomized to 4 weeks of exercise training or sedentary lifestyle. Endothelial function of the radial artery is determined...
Eligibility Criteria
Inclusion
- stable CAD
- male gender
Exclusion
- insulin-dependent diabetes mellitus
- significant valvular heart disease
- smoking
- exercise-induced myocardial ischemia
- conditions prohibiting exercise training
Key Trial Info
Start Date :
January 1 2001
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00176345
Start Date
January 1 2001
Last Update
September 15 2005
Active Locations (1)
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1
University of Leipzig, Heart Center, Department of Internal Medicine / Cardiology
Leipzig, Saxony, Germany, 04289