Status:
COMPLETED
A Study For Using Radiosurgery On Limited Metastases
Lead Sponsor:
University of Rochester
Conditions:
Neoplasms, Metastatic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The standard therapy in cases such as yours is surgery, radiation therapy, chemotherapy or hormonal therapy alone or in combination. The main purpose of this study is to evaluate whether radiosurgery ...
Detailed Description
In this research study high dose stereotactic body radiation therapy will be directed at the site of metastasis. This treatment will be given once a day, 5 times a week (Monday through Friday) for one...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- KPS ≥ 70
- Palliative: Disease most likely to be life limiting, is definable, and treatable to a sterilizing dose according to protocol criteria.
- The size of the lesion must be such that it can be safely treated to sterilizing radiation doses according to the rules in the protocol
- Previously treated lesions are not eligible unless the prescribed dose can be safely delivered. Previously enrolled patients can be retreated to new lesions if they still meet protocol requirements.
- Informed consent must be obtained.
- Pregnancy test must be negative for women of child bearing potential.
- Out of state patients are eligible, if communication with the referring physicians is expected to be adequate to address the primary aim. The secondary aim (blood cytokines) is optional for out-of-state patients.
Exclusion
- Technical inability to achieve required dose based on safe dose constraints required for radiosurgery
- Women who are pregnant or nursing..
- Failure to meet inclusion requirements
- Contraindications to radiation.
- Patient should not be eligible for primary disease specific radiosurgical protocols
Key Trial Info
Start Date :
April 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2007
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT00178399
Start Date
April 1 2001
End Date
March 15 2007
Last Update
October 11 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Rochester Department of Radiation Oncology
Rochester, New York, United States, 14642