Status:

COMPLETED

Covalent Tolerance Induction to Factor VIII-Prediction of Inhibitors in Hemophilia

Lead Sponsor:

The University of Texas Health Science Center, Houston

Conditions:

Hemophilia A

Eligibility:

MALE

1-99 years

Brief Summary

To correlate the Human Leukocyte Antigen type and genetic defect with hemophilia A.

Detailed Description

One of the most serious complications of treatment in patients with hemophilia A or hemophilia B is the development of an inhibitor, which is an antibody that neutralizes the factor VIII or IX coagula...

Eligibility Criteria

Inclusion

  • Severe Hemophilia A with an inhibitor level of 0.6 B.U. or higher

Exclusion

  • Severe Hemophilia A with a negative inhibitor

Key Trial Info

Start Date :

August 1 2002

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2015

Estimated Enrollment :

99 Patients enrolled

Trial Details

Trial ID

NCT00178607

Start Date

August 1 2002

End Date

October 1 2015

Last Update

May 12 2016

Active Locations (1)

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1

The Univeristy of Texas Health Science Center at Houston

Houston, Texas, United States, 77030