Status:

COMPLETED

Effects of Soy Isoflavones on Menopausal Hot Flashes

Lead Sponsor:

Beth Israel Deaconess Medical Center

Collaborating Sponsors:

Nichimo - Tokyo, Japan

Conditions:

Menopausal Symptoms

Eligibility:

FEMALE

38-65 years

Phase:

PHASE2

PHASE3

Brief Summary

Hot flashes occur in three quarters of menopausal women, and can negatively impact quality of life. Interest has arisen in isoflavones, found in rich supply in soy products, as therapy for hot flashes...

Detailed Description

Hot flashes occur in 75% of menopausal women and impact quality of life. Interest has arisen in isoflavones, found in rich supply in soy products, as therapy for hot flashes. The effect of a daidzein-...

Eligibility Criteria

Inclusion

  • No menstrual period for at least six months, Hot flashes at least four t imes per day, Ages 38-65

Exclusion

  • Pregnant, BMI\>45, History of breast cancer or other estrogen dependent tumors, Abnormal uterine bleeding, Heart, renal, or liver disease, Diabetes, Women taking hormone replacement therapy or serotonin reuptake inhibitors, Women taking any dietary supplements for the treatment of hot flashes (ex. soy supplements, vitamin E, flaxseed, red clover extract) within the past 30 days

Key Trial Info

Start Date :

June 1 2003

Trial Type :

INTERVENTIONAL

End Date :

September 1 2005

Estimated Enrollment :

210 Patients enrolled

Trial Details

Trial ID

NCT00179556

Start Date

June 1 2003

End Date

September 1 2005

Last Update

March 14 2017

Active Locations (1)

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1

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215