Status:
COMPLETED
Maternal KIR and Fetal HLA-C Genes in Recurrent Miscarriages
Lead Sponsor:
Imperial College London
Conditions:
Recurrent Miscarriages
Eligibility:
All Genders
Brief Summary
For implantation of developing conceptus, placental cells need to invade mother's uterus to access maternal blood supply in a control manner. We have found a combination of maternal immune genes (the ...
Detailed Description
Little is known about reasons for early pregnancy failures. It is believed that some pathology leading to defective implantation of fetus in maternal uterus may lead to recurrent early miscarriages. T...
Eligibility Criteria
Inclusion
- Couples with 3 or more unexplained miscarriages
Exclusion
- Previous livebirths, parental karyotypic abnormalities, thrombophilic defects, uterine structural abnormalities
Key Trial Info
Start Date :
April 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2005
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT00180804
Start Date
April 1 2005
End Date
August 31 2005
Last Update
October 16 2023
Active Locations (1)
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1
St. Mary's Hospital
London, United Kingdom, W2 1NY