Status:
COMPLETED
Premature Infants in Need of Transfusion (PINT)
Lead Sponsor:
McMaster University
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Anemia of Prematurity
Eligibility:
All Genders
Up to 48 years
Phase:
PHASE3
Brief Summary
Hypothesis: That a high hemoglobin threshold for transfusion in extremely low birth weight (ELBW) infants is associated with a lower rate of survival without severe morbidity (defined as one or more o...
Eligibility Criteria
Inclusion
- birth weight \<1000g
- postnatal age \<48 hours
- no transfusion beyond first 6 hours of life
- estimated gestational age of 30 completed weeks or less
Exclusion
- infant considered non-viable by attending physician
- infant has cyanotic congenital heart disease
- infant's parents known to be opposed to blood transfusion
- either parent has hemoglobinopathies or congenital anemias
- infant has hemolytic disease
- infant has severe acute hemorrhage, severe shock, severe sepsis with coagulopathy or requires peri-operative transfusion
- prior treatment with or intention to treat with erythropoietin
Key Trial Info
Start Date :
February 1 2001
Trial Type :
INTERVENTIONAL
End Date :
November 1 2005
Estimated Enrollment :
424 Patients enrolled
Trial Details
Trial ID
NCT00182390
Start Date
February 1 2001
End Date
November 1 2005
Last Update
September 24 2015
Active Locations (10)
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1
Albany Medical Center
Albany, New York, United States, 12208
2
Brooklyn Hospital Center
Brooklyn, New York, United States, 11201
3
Royal Women's Hospital
Melbourne, Victoria, Australia, 3053
4
Mercy Hospital for Women
Melbourne, Victoria, Australia, 3084