Status:

COMPLETED

LOMA: Long-Term Management of Asthma

Lead Sponsor:

Hamilton Health Sciences Corporation

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Asthma

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

The purpose of this study was to determine whether the use of induced sputum cell counts could guide treatment of asthma more effectively than the use of symptoms and breathing tests. The main outcome...

Detailed Description

Airway inflammation is an important component of asthma. It influences other components which include symptoms and airway functional (physiological) measurements. It is the primary target of treatment...

Eligibility Criteria

Inclusion

  • History of asthma for at least one year,confirmed objectively.
  • New or previously reviewed patients where the minimal treatment requirements have not been established within the last six months.

Exclusion

  • Smokers or ex-smokers for less than 6 months with a smoking history of more than 10 pack years.
  • Other pulmonary co-morbidity (other than mild or moderate chronic airflow limitation).
  • Subjects having a co-existing illness that precludes them from the study.
  • Inability to give informed consent due to mental or legal reasons.
  • Pregnancy or lactation.
  • Known non-compliance with medications.

Key Trial Info

Start Date :

September 1 1999

Trial Type :

INTERVENTIONAL

End Date :

September 1 2001

Estimated Enrollment :

112 Patients enrolled

Trial Details

Trial ID

NCT00182481

Start Date

September 1 1999

End Date

September 1 2001

Last Update

December 16 2005

Active Locations (1)

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1

Firestone Institute for Respiratory Health, St. Joseph's Healthcare

Hamilton, Ontario, Canada, L8N 4A6