Status:
COMPLETED
Blockade of Vascular Potassium Channels During Human Endotoxemia
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
ZonMw: The Netherlands Organisation for Health Research and Development
Conditions:
Endotoxemia
Eligibility:
All Genders
18-35 years
Phase:
PHASE1
Brief Summary
Background: Activation of NO-synthase and vascular potassium (K) channels may play a role in the sepsis-induced attenuated sensitivity to norepinephrine. We examined whether various K channel blockers...
Eligibility Criteria
Inclusion
- healthy volunteers
Exclusion
- drug, alcohol, nicotine abuse
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2005
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00185003
Start Date
January 1 2003
End Date
June 1 2005
Last Update
October 17 2008
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